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BAKU, Azerbaijan, Feb. 10
By Nargiz Sadikhova – Trend:
CoronaVac anti-COVID vaccine is safe and well-tolerated in older adults, the study finds, Trend reports citing the Lance Infectious Diseases Journal.
In an article named “Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy adults aged 60 years and older: a randomized, double-blind, placebo-controlled, phase 1/2 clinical trial” the reporters write that a vaccine against COVID-19 is urgently needed for older adults, in whom morbidity and mortality due to the disease are increased.
“We aimed to assess the safety, tolerability, and immunogenicity of a candidate COVID-19 vaccine, CoronaVac, containing inactivated SARS-CoV-2, in adults aged 60 years and older,” the report said.
The method used in the research was a randomized, double-blind, placebo-controlled, phase 1/2 clinical trial of CoronaVac in healthy adults aged 60 years and older in Renqiu (Hebei, China). Vaccine or placebo was given by intramuscular injection in two doses (days 0 and 28).
The study found that CoronaVac is safe and well-tolerated in older adults.
“Neutralising antibody titers induced by the 3 μg dose were similar to those of the 6 μg dose, and higher than those of the 1·5 μg dose, supporting the use of the 3 μg dose CoronaVac in phase 3 trials to assess protection against COVID-19,” the report said.
The study was funded by the Chinese National Key Research and Development Program and Beijing Science and Technology Program.
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