Police in the university town of Boulder say they have responded to the incident at the King Soopers super market.
A law enforcement source told ABC News that officers responded to a report of someone being shot in the store’s car park, and were in turn fired upon by a suspect.
“ALERT: Active Shooter at the King Soopers on Table Mesa. AVOID THE AREA. PIO is en-route,” tweeted Boulder Police Department just before 3pm local time.
Jefferson County Sheriff’s Office says they have deployed SWAT to the scene.
A witness told FOX31 that they had seen a man in the car park dressed in tactical gear and carrying an “AR-15 style weapon.”
The King Soopers grocery store on Table Mesa is two miles south of the University of Colorado Boulder campus.
Video from the scene showed police surrounding the building as someone could be heard over the loudspeaker saying, “This is the Boulder Police Department … come out with your hands up.”
Police could then be seen removing a shirtless man with a blood covered leg from the scene in handcuffs but it is unclear if he is a suspect.